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Overlap in signaling between Smoothened and the α subunit of the heterotrimeric G protein G(13)
The Hedgehog family of morphogens has long been known to utilize, through the 7-transmembrane protein Smoothened (Smo), the heterotrimeric G protein G(i) in both canonical and noncanonical forms of signaling. Other G proteins, while not specifically utilized by Smo, may nonetheless provide access to...
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| Udgivet i: | PLoS One |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5953476/ https://ncbi.nlm.nih.gov/pubmed/29763457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197442 |
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