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Dynamic Coupling and Allosteric Networks in the α Subunit of Heterotrimeric G Proteins
G protein α subunits cycle between active and inactive conformations to regulate a multitude of intracellular signaling cascades. Important structural transitions occurring during this cycle have been characterized from extensive crystallographic studies. However, the link between observed conformat...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4813496/ https://ncbi.nlm.nih.gov/pubmed/26703464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.702605 |
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