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Dynamic Coupling and Allosteric Networks in the α Subunit of Heterotrimeric G Proteins

G protein α subunits cycle between active and inactive conformations to regulate a multitude of intracellular signaling cascades. Important structural transitions occurring during this cycle have been characterized from extensive crystallographic studies. However, the link between observed conformat...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Biol Chem
Κύριοι συγγραφείς: Yao, Xin-Qiu, Malik, Rabia U., Griggs, Nicholas W., Skjærven, Lars, Traynor, John R., Sivaramakrishnan, Sivaraj, Grant, Barry J.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813496/
https://ncbi.nlm.nih.gov/pubmed/26703464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.702605
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