A Conserved Phenylalanine as a Relay between the α5 Helix and the GDP Binding Region of Heterotrimeric G(i) Protein α Subunit

G protein activation by G protein-coupled receptors is one of the critical steps for many cellular signal transduction pathways. Previously, we and other groups reported that the α5 helix in the G protein α subunit plays a major role during this activation process. However, the precise signaling pat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kaya, Ali I., Lokits, Alyssa D., Gilbert, James A., Iverson, Tina M., Meiler, Jens, Hamm, Heidi E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2014
Pynciau:
Signal Transduction
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148873/
https://ncbi.nlm.nih.gov/pubmed/25037222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.572875
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg