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A Conserved Phenylalanine as a Relay between the α5 Helix and the GDP Binding Region of Heterotrimeric G(i) Protein α Subunit
G protein activation by G protein-coupled receptors is one of the critical steps for many cellular signal transduction pathways. Previously, we and other groups reported that the α5 helix in the G protein α subunit plays a major role during this activation process. However, the precise signaling pat...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4148873/ https://ncbi.nlm.nih.gov/pubmed/25037222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.572875 |
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