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A Conserved Hydrophobic Core in Gα(i1) Regulates G Protein Activation and Release from Activated Receptor
G protein-coupled receptor-mediated heterotrimeric G protein activation is a major mode of signal transduction in the cell. Previously, we and other groups reported that the α5 helix of Gα(i1), especially the hydrophobic interactions in this region, plays a key role during nucleotide release and G p...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5016700/ https://ncbi.nlm.nih.gov/pubmed/27462082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.745513 |
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