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Linking receptor activation to changes in Sw I and II of Gα proteins
G-protein coupled receptors catalyze nucleotide exchange on G proteins, which results in subunit dissociation and effector activation. In the recent β(2)AR-G(s) structure, portions of Switch I and II of Gα are not fully elucidated. We paired fluorescence studies of receptor-Gα(i) interactions with t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726552/ https://ncbi.nlm.nih.gov/pubmed/23466875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2013.02.016 |
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