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Receptor-mediated changes at the myristoylated amino terminus of Gα(il) proteins

GPCRs catalyze nucleotide release in heterotrimeric G proteins, the slow step in G protein activation. G(i/o) family proteins are permanently, cotranslationally myristoylated at the extreme amino terminus. While myristoylation of the amino terminus has long been known to participate in anchoring G(i...

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Detalles Bibliográficos
Main Authors: Preininger, Anita M., Parello, Joseph, Meier, Scott M., Liao, Guihua, Hamm, Heidi E.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751642/
https://ncbi.nlm.nih.gov/pubmed/18771287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800741r
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