Chargement en cours...
Myristoylation exerts direct and allosteric effects on Gα conformation and dynamics in solution
Coupling of heterotrimeric G proteins to activated G protein-coupled receptors results in nucleotide exchange on the Gα subunit, which in turn decreases its affinity for both Gβγ and activated receptors. N-terminal myristoylation of Gα subunits aids in membrane localization of inactive G proteins. D...
Enregistré dans:
| Auteurs principaux: | , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3312377/ https://ncbi.nlm.nih.gov/pubmed/22329346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201472c |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|