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Conformational flexibility and structural dynamics in GPCR-mediated G protein activation: a perspective

Structure and dynamics of G proteins and their cognate receptors, both alone and in complex, are becoming increasingly accessible to experimental techniques. Understanding the conformational changes and timelines which govern these changes can lead to new insights into the processes of ligand bindin...

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Detalhes bibliográficos
Main Authors: Preininger, Anita M., Meiler, Jens, Hamm, Heidi
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686903/
https://ncbi.nlm.nih.gov/pubmed/23602809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.04.011
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