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Trp fluorescence reveals an activation-dependent cation-π interaction in the Switch II region of Gα(i) proteins
Crystal structures of Gα(i) (and closely related family member Gα(t)) reveal much of what we currently know about G protein structure, including changes which occur in Switch regions. Gα(t) exhibits a low rate of basal (uncatalyzed) nucleotide exchange and an ordered Switch II region in the GDP-boun...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2788287/ https://ncbi.nlm.nih.gov/pubmed/19760664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.243 |
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