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The 2.7-Å crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase

The x-ray crystal structure of a 194-kDa fragment from module 5 of the 6-deoxyerythronolide B synthase has been solved at 2.7 Å resolution. Each subunit of the homodimeric protein contains a full-length ketosynthase (KS) and acyl transferase (AT) domain as well as three flanking “linkers.” The linke...

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Detalhes bibliográficos
Main Authors: Tang, Yinyan, Kim, Chu-Young, Mathews, Irimpan I., Cane, David E., Khosla, Chaitan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636687/
https://ncbi.nlm.nih.gov/pubmed/16844787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601924103
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