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Consequences of Copper Accumulation in the Livers of the Atp7b(−/−) (Wilson Disease Gene) Knockout Mice
Wilson disease is a severe genetic disorder associated with intracellular copper overload. The affected gene, ATP7B, has been identified, but the molecular events leading to Wilson disease remain poorly understood. Here, we demonstrate that genetically engineered Atp7b(−/−) mice represent a valuable...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Investigative Pathology
2006
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1606493/ https://ncbi.nlm.nih.gov/pubmed/16436657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050312 |
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