ELEVATED COPPER REMODELS HEPATIC RNA PROCESSING MACHINERY IN THE MOUSE MODEL OF WILSON'S DISEASE

Copper is essential to mammalian physiology and its homeostasis is tightly regulated. In humans, genetic defects in copper excretion result in copper overload and Wilson's disease (WD). Previous studies in the mouse model for WD (Atp7b(-/-)) revealed copper accumulation in hepatic nuclei and sp...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Burkhead, Jason L., Ralle, Martina, Wilmarth, Phillip, David, Larry, Lutsenko, Svetlana
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033566/
https://ncbi.nlm.nih.gov/pubmed/21146535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.12.001
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados