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A systems approach implicates nuclear receptor targeting in the Atp7b(−/−) mouse model of Wilson’s Disease

Wilson’s disease (WD) is an inherited disorder of copper metabolism characterized by liver disease and/or neurologic and psychiatric pathology. The disease is a result of mutation in ATP7B, which encodes the ATP7B copper transporting ATPase. Loss of copper transport function by ATP7B results in copp...

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Detalhes bibliográficos
Main Authors: Wilmarth, Phillip, Short, Kristopher, Fiehn, Oliver, Lutsenko, Svetlana, David, Larry, Burkhead, Jason L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695828/
https://ncbi.nlm.nih.gov/pubmed/22565294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2mt20017a
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