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Positron Emission Tomography of Copper Metabolism in the Atp7b(−/−) Knock-out Mouse Model of Wilson’s Disease

PURPOSE: This study aims to determine feasibility and utility of copper-64(II) chloride ((64)CuCl(2)) as a tracer for positron emission tomography (PET) of copper metabolism imbalance in human Wilson’s disease (WD). PROCEDURES: Atp7b(−/−) mice, a mouse model of human WD, were injected with (64)CuCl(...

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Detalhes bibliográficos
Main Authors: Peng, Fangyu, Lutsenko, Svetlana, Sun, Xiankai, Muzik, Otto
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157550/
https://ncbi.nlm.nih.gov/pubmed/21327972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-011-0476-4
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