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Age-dependent Changes of Cerebral Copper Metabolism in Atp7b(−/−) Knockout Mouse Model of Wilson’s Disease by [(64)Cu]CuCl(2)-PET/CT

Copper is a nutritional metal required for brain development and function. Wilson’s disease (WD), or hepatolenticular degeneration, is an inherited human copper metabolism disorder caused by mutation of ATP7B gene. Many WD patients present with variable neurological and psychiatric symptoms, which m...

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Bibliografiset tiedot
Julkaisussa:Metab Brain Dis
Päätekijät: Xie, Fang, Xi, Yin, Pascual, Juan M., Muzik, Otto, Peng, Fangyu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573586/
https://ncbi.nlm.nih.gov/pubmed/28130615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11011-017-9956-9
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