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Age-dependent Changes of Cerebral Copper Metabolism in Atp7b(−/−) Knockout Mouse Model of Wilson’s Disease by [(64)Cu]CuCl(2)-PET/CT
Copper is a nutritional metal required for brain development and function. Wilson’s disease (WD), or hepatolenticular degeneration, is an inherited human copper metabolism disorder caused by mutation of ATP7B gene. Many WD patients present with variable neurological and psychiatric symptoms, which m...
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| Publicado no: | Metab Brain Dis |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5573586/ https://ncbi.nlm.nih.gov/pubmed/28130615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11011-017-9956-9 |
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