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Age-dependent Changes of Cerebral Copper Metabolism in Atp7b(−/−) Knockout Mouse Model of Wilson’s Disease by [(64)Cu]CuCl(2)-PET/CT

Copper is a nutritional metal required for brain development and function. Wilson’s disease (WD), or hepatolenticular degeneration, is an inherited human copper metabolism disorder caused by mutation of ATP7B gene. Many WD patients present with variable neurological and psychiatric symptoms, which m...

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Bibliografske podrobnosti
izdano v:Metab Brain Dis
Main Authors: Xie, Fang, Xi, Yin, Pascual, Juan M., Muzik, Otto, Peng, Fangyu
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573586/
https://ncbi.nlm.nih.gov/pubmed/28130615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11011-017-9956-9
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