The antipsychotic drug chlorpromazine inhibits HERG potassium channels

1. Acquired long QT syndrome (aLQTS) is caused by prolongation of the cardiac action potential because of blockade of cardiac ion channels and delayed repolarization of the heart. Patients with aLQTS carry an increased risk for torsade de pointes arrhythmias and sudden cardiac death. Several antipsy...

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Bibliografiske detaljer
Main Authors: Thomas, Dierk, Wu, Kezhong, Kathöfer, Sven, Katus, Hugo A, Schoels, Wolfgang, Kiehn, Johann, Karle, Christoph A
Format: Artigo
Sprog:Inglês
Udgivet: 2003
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Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573882/
https://ncbi.nlm.nih.gov/pubmed/12788816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705283
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