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The antipsychotic drug chlorpromazine inhibits HERG potassium channels

1. Acquired long QT syndrome (aLQTS) is caused by prolongation of the cardiac action potential because of blockade of cardiac ion channels and delayed repolarization of the heart. Patients with aLQTS carry an increased risk for torsade de pointes arrhythmias and sudden cardiac death. Several antipsy...

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Détails bibliographiques
Auteurs principaux: Thomas, Dierk, Wu, Kezhong, Kathöfer, Sven, Katus, Hugo A, Schoels, Wolfgang, Kiehn, Johann, Karle, Christoph A
Format: Artigo
Langue:Inglês
Publié: 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573882/
https://ncbi.nlm.nih.gov/pubmed/12788816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705283
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