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The antipsychotic drug chlorpromazine inhibits HERG potassium channels

1. Acquired long QT syndrome (aLQTS) is caused by prolongation of the cardiac action potential because of blockade of cardiac ion channels and delayed repolarization of the heart. Patients with aLQTS carry an increased risk for torsade de pointes arrhythmias and sudden cardiac death. Several antipsy...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Thomas, Dierk, Wu, Kezhong, Kathöfer, Sven, Katus, Hugo A, Schoels, Wolfgang, Kiehn, Johann, Karle, Christoph A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573882/
https://ncbi.nlm.nih.gov/pubmed/12788816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705283
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