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Bertosamil blocks HERG potassium channels in their open and inactivated states
1. Bertosamil is chemically related to the class-III anti-arrhythmic drug tedisamil and has been developed as a bradycardic, anti-ischemic and anti-arrhythmic drug. Its anti-arrhythmic properties might in part be attributed to its block of voltage-dependent potassium channels Kv(1.2), Kv(1.4). and K...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573484/ https://ncbi.nlm.nih.gov/pubmed/12208779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704859 |
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