Acute effects of dronedarone on both components of the cardiac delayed rectifier K(+) current, HERG and KvLQT1/minK potassium channels

1. Dronedarone is a noniodinated benzofuran derivative that has been synthesized to overcome the limiting iodine-associated adverse effects of the potent antiarrhythmic drug amiodarone. In this study, the acute electrophysiological effects of dronedarone on repolarizing potassium channels were inves...

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Main Authors: Thomas, Dierk, Kathöfer, Sven, Zhang, Wei, Wu, Kezhong, Wimmer, Anna-Britt, Zitron, Edgar, Kreye, Volker A W, Katus, Hugo A, Schoels, Wolfgang, Karle, Christoph A, Kiehn, Johann
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574095/
https://ncbi.nlm.nih.gov/pubmed/14517175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705502
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