Keratin 8 and 18 mutations are risk factors for developing liver disease of multiple etiologies

Keratin 8 and 18 (K8/K18) mutations are found in patients with cryptogenic cirrhosis, but the role of keratin mutations in noncryptogenic cirrhosis and the incidence of keratin mutations in the general population are not known. We screened for K8/K18 mutations in genomic DNA isolated from 314 liver...

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Main Authors: Ku, Nam-On, Darling, Jama M., Krams, Sheri M., Esquivel, Carlos O., Keeffe, Emmet B., Sibley, Richard K., Lee, Young Moo, Wright, Teresa L., Omary, M. Bishr
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC156326/
https://ncbi.nlm.nih.gov/pubmed/12724528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0936165100
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