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Keratins Turn over by Ubiquitination in a Phosphorylation-Modulated Fashion

Keratin polypeptides 8 and 18 (K8/18) are intermediate filament (IF) proteins that are expressed in glandular epithelia. Although the mechanism of keratin turnover is poorly understood, caspase-mediated degradation of type I keratins occurs during apoptosis and the proteasome pathway has been indire...

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Autori principali: Ku, Nam-On, Omary, M. Bishr
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174842/
https://ncbi.nlm.nih.gov/pubmed/10791969
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