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Keratin binding to 14-3-3 proteins modulates keratin filaments and hepatocyte mitotic progression

Keratin polypeptides 8 and 18 (K8/18) are the major intermediate filament proteins of simple-type epithelia. K18 Ser-33 phosphorylation regulates its binding to 14-3-3 proteins during mitosis. We studied the significance of keratin binding to 14-3-3 in transgenic mice that overexpress wild-type or S...

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Detalhes bibliográficos
Main Authors: Ku, Nam-On, Michie, Sara, Resurreccion, Evelyn Z., Broome, Rosemary L., Omary, M. Bishr
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123655/
https://ncbi.nlm.nih.gov/pubmed/11917136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.072624299
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