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Absence of keratins 8 and 18 expression in rodent epithelial cell lines associates with keratin gene mutation and DNA methylation: cell line selective effects on cell invasion

Epithelial-mesenchymal transition (EMT) in carcinoma is associated with dramatic up-regulation of vimentin and down-regulation of the simple-type keratins 8 and 18 (K8/K18), but the mechanisms of these changes are poorly understood. We demonstrate that two commonly-studied murine (CT26) and rat (IEC...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Exp Cell Res
मुख्य लेखकों: Kwan, Raymond, Looi, Kok Sun, Omary, M. Bishr
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921235/
https://ncbi.nlm.nih.gov/pubmed/25882495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2015.04.003
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