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Toward unraveling the complexity of simple epithelial keratins in human disease

Simple epithelial keratins (SEKs) are found primarily in single-layered simple epithelia and include keratin 7 (K7), K8, K18–K20, and K23. Genetically engineered mice that lack SEKs or overexpress mutant SEKs have helped illuminate several keratin functions and served as important disease models. In...

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Autors principals: Omary, M. Bishr, Ku, Nam-On, Strnad, Pavel, Hanada, Shinichiro
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701867/
https://ncbi.nlm.nih.gov/pubmed/19587454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37762
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