Keratin 8 and 18 mutations are risk factors for developing liver disease of multiple etiologies

Keratin 8 and 18 (K8/K18) mutations are found in patients with cryptogenic cirrhosis, but the role of keratin mutations in noncryptogenic cirrhosis and the incidence of keratin mutations in the general population are not known. We screened for K8/K18 mutations in genomic DNA isolated from 314 liver...

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Autors principals: Ku, Nam-On, Darling, Jama M., Krams, Sheri M., Esquivel, Carlos O., Keeffe, Emmet B., Sibley, Richard K., Lee, Young Moo, Wright, Teresa L., Omary, M. Bishr
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2003
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC156326/
https://ncbi.nlm.nih.gov/pubmed/12724528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0936165100
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