Llwytho...

Raf-1 activation disrupts its binding to keratins during cell stress

Keratins 8 and 18 (K8/18) heteropolymers may regulate cell signaling via the known K18 association with 14-3-3 proteins and 14-3-3 association with Raf-1 kinase. We characterized Raf–keratin–14-3-3 associations and show that Raf associates directly with K8, independent of Raf kinase activity or Ras–...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ku, Nam-On, Fu, Haian, Omary, M. Bishr
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172217/
https://ncbi.nlm.nih.gov/pubmed/15314064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200402051
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