Increased islet apoptosis in Pdx1(+/–) mice

Mice with 50% Pdx1, a homeobox gene critical for pancreatic development, had worsening glucose tolerance with age and reduced insulin release in response to glucose, KCl, and arginine from the perfused pancreas. Surprisingly, insulin secretion in perifusion or static incubation experiments in respon...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Johnson, James D., Ahmed, Noreen T., Luciani, Dan S., Han, Zhiqiang, Tran, Hung, Fujita, Jun, Misler, Stanley, Edlund, Helena, Polonsky, Kenneth S.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2003
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC152933/
https://ncbi.nlm.nih.gov/pubmed/12697734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200316537
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires