Increased islet apoptosis in Pdx1(+/–) mice

Mice with 50% Pdx1, a homeobox gene critical for pancreatic development, had worsening glucose tolerance with age and reduced insulin release in response to glucose, KCl, and arginine from the perfused pancreas. Surprisingly, insulin secretion in perifusion or static incubation experiments in respon...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Johnson, James D., Ahmed, Noreen T., Luciani, Dan S., Han, Zhiqiang, Tran, Hung, Fujita, Jun, Misler, Stanley, Edlund, Helena, Polonsky, Kenneth S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2003
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC152933/
https://ncbi.nlm.nih.gov/pubmed/12697734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200316537
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars