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Heat-Aggregated Noninfectious Influenza Virus Induces a More Balanced CD8(+)-T-Lymphocyte Immunodominance Hierarchy Than Infectious Virus
CD8(+)-T-cell (T(CD8+)) responses to infectious viruses are characterized by an immunodominance hierarchy in which the majority of T(CD8+) respond to one or a few immunodominant determinants, with a minority of T(CD8+) responding to a number of subdominant determinants. It is now well established th...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC152137/ https://ncbi.nlm.nih.gov/pubmed/12663774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.8.4679-4684.2003 |
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