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Immunoproteasomes Shape Immunodominance Hierarchies of Antiviral Cd8(+) T Cells at the Levels of T Cell Repertoire and Presentation of Viral Antigens

Vertebrates express three cytokine-inducible proteasome subunits that are incorporated in the place of their constitutively synthesized counterparts. There is increasing evidence that the set of peptides generated by proteasomes containing these subunits (immunoproteasomes) differs from that produce...

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Autors principals: Chen, Weisan, Norbury, Christopher C., Cho, Yunjung, Yewdell, Jonathan W., Bennink, Jack R.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193381/
https://ncbi.nlm.nih.gov/pubmed/11390439
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