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Unexpected Role for the Immunoproteasome Subunit LMP2 in Antiviral Humoral and Innate Immune Responses

Proteasomes are multisubunit proteases that initiate degradation of many Ags presented by MHC class I molecules. Vertebrates express alternate forms of each of the three catalytic proteasome subunits: standard subunits, and immunosubunits, which are constitutively expressed by APCs and are induced i...

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Detalhes bibliográficos
Main Authors: Hensley, Scott E., Zanker, Damien, Dolan, Brian P., David, Alexandre, Hickman, Heather D., Embry, Alan C., Skon, Cara N., Grebe, Kristie M., Griffin, Thomas A., Chen, Weisan, Bennink, Jack R., Yewdell, Jonathan W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941094/
https://ncbi.nlm.nih.gov/pubmed/20228196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903003
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