Unexpected Role for the Immunoproteasome Subunit LMP2 in Antiviral Humoral and Innate Immune Responses

Proteasomes are multisubunit proteases that initiate degradation of many Ags presented by MHC class I molecules. Vertebrates express alternate forms of each of the three catalytic proteasome subunits: standard subunits, and immunosubunits, which are constitutively expressed by APCs and are induced i...

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Main Authors: Hensley, Scott E., Zanker, Damien, Dolan, Brian P., David, Alexandre, Hickman, Heather D., Embry, Alan C., Skon, Cara N., Grebe, Kristie M., Griffin, Thomas A., Chen, Weisan, Bennink, Jack R., Yewdell, Jonathan W.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941094/
https://ncbi.nlm.nih.gov/pubmed/20228196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903003
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