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Mixed Proteasomes Function To Increase Viral Peptide Diversity and Broaden Antiviral CD8(+) T Cell Responses
The three proteasome subunits with proteolytic activity are encoded by standard or immunoproteasome genes. Many proteasomes expressed by normal cells and cells exposed to cytokines are “mixed”, that is, contain both standard and immunoproteasome subunits. Using a panel of 38 defined influenza A viru...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3762975/ https://ncbi.nlm.nih.gov/pubmed/23709680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300802 |
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