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Mixed Proteasomes Function To Increase Viral Peptide Diversity and Broaden Antiviral CD8(+) T Cell Responses

The three proteasome subunits with proteolytic activity are encoded by standard or immunoproteasome genes. Many proteasomes expressed by normal cells and cells exposed to cytokines are “mixed”, that is, contain both standard and immunoproteasome subunits. Using a panel of 38 defined influenza A viru...

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Detalhes bibliográficos
Main Authors: Zanker, Damien, Waithman, Jason, Yewdell, Jonathan W., Chen, Weisan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762975/
https://ncbi.nlm.nih.gov/pubmed/23709680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300802
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