Contribution of proteasome-catalyzed peptide cis-splicing to viral targeting by CD8(+) T cells in HIV-1 infection

Peptides generated by proteasome-catalyzed splicing of noncontiguous amino acid sequences have been shown to constitute a source of nontemplated human leukocyte antigen class I (HLA-I) epitopes, but their role in pathogen-specific immunity remains unknown. CD8(+) T cells are key mediators of HIV typ...

詳細記述

保存先:
書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Paes, Wayne, Leonov, German, Partridge, Thomas, Chikata, Takayuki, Murakoshi, Hayato, Frangou, Anna, Brackenridge, Simon, Nicastri, Annalisa, Smith, Andrew G., Learn, Gerald H., Li, Yingying, Parker, Robert, Oka, Shinichi, Pellegrino, Pierre, Williams, Ian, Haynes, Barton F., McMichael, Andrew J., Shaw, George M., Hahn, Beatrice H., Takiguchi, Masafumi, Ternette, Nicola, Borrow, Persephone
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2019
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900506/
https://ncbi.nlm.nih.gov/pubmed/31748275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911622116
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