Contribution of proteasome-catalyzed peptide cis-splicing to viral targeting by CD8(+) T cells in HIV-1 infection

Peptides generated by proteasome-catalyzed splicing of noncontiguous amino acid sequences have been shown to constitute a source of nontemplated human leukocyte antigen class I (HLA-I) epitopes, but their role in pathogen-specific immunity remains unknown. CD8(+) T cells are key mediators of HIV typ...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Paes, Wayne, Leonov, German, Partridge, Thomas, Chikata, Takayuki, Murakoshi, Hayato, Frangou, Anna, Brackenridge, Simon, Nicastri, Annalisa, Smith, Andrew G., Learn, Gerald H., Li, Yingying, Parker, Robert, Oka, Shinichi, Pellegrino, Pierre, Williams, Ian, Haynes, Barton F., McMichael, Andrew J., Shaw, George M., Hahn, Beatrice H., Takiguchi, Masafumi, Ternette, Nicola, Borrow, Persephone
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2019
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900506/
https://ncbi.nlm.nih.gov/pubmed/31748275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911622116
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