Role of Escape Mutant-Specific T Cells in Suppression of HIV-1 Replication and Coevolution with HIV-1

The accumulation of HIV-1 escape mutations affects HIV-1 control by HIV-1-specific T cells. Some of these mutations can elicit escape mutant-specific T cells, but it still remains unclear whether they can suppress the replication of HIV-1 mutants. It is known that HLA-B*52:01-restricted RI8 (Gag 275...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Zhang, Yu, Kuse, Nozomi, Akahoshi, Tomohiro, Chikata, Takayuki, Gatanaga, Hiroyuki, Oka, Shinichi, Murakoshi, Hayato, Takiguchi, Masafumi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7495385/
https://ncbi.nlm.nih.gov/pubmed/32699092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01151-20
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