Impact of a single HLA-A*24:02-associated escape mutation on the detrimental effect of HLA-B*35:01 in HIV-1 control

BACKGROUND: HLA-B*35 is an HLA allele associated with rapid progression to AIDS. However, a mechanism underlying the detrimental effect of HLA-B*35 on disease outcome remains unknown. Recent studies demonstrated that most prevalent subtype HLA-B*35:01 is a detrimental allele in HIV-1 clade B-infecte...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Murakoshi, Hayato, Koyanagi, Madoka, Akahoshi, Tomohiro, Chikata, Takayuki, Kuse, Nozomi, Gatanaga, Hiroyuki, Rowland-Jones, Sarah L., Oka, Shinichi, Takiguchi, Masafumi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197679/
https://ncbi.nlm.nih.gov/pubmed/30249546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.09.022
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