ロード中...
Terminal Deoxynucleotidyl Transferase Establishes and Broadens Anti-Viral CD8(+) T Cell Immunodominance Hierarchies
The action of terminal deoxynucleotidyl transferase (TdT) on mouse T cell receptor (TCR) genes accounts for ∼ 90% of T cell repertoire diversity. We report that in TdT -/- mice, total T(CD8+) responses to influenza and vaccinia viruses are reduced by ∼ 30% relative to wt mice. We find that T(CD8+) r...
保存先:
| 主要な著者: | , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587314/ https://ncbi.nlm.nih.gov/pubmed/18566432 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|