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Co-Inhibition of the Immunoproteasome Subunits LMP2 and LMP7 Ameliorates Immune Thrombocytopenia

The immunoproteasome, a special isoform of the 20S proteasome, is expressed when the cells receive an inflammatory signal. Immunoproteasome inhibition proved efficacy in the treatment of autoimmune diseases. However, the role of the immunoproteasome in the pathogenesis of immune thrombocytopenia (IT...

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Podrobná bibliografie
Vydáno v:Front Immunol
Hlavní autoři: Du, Sheng-hong, Xiang, Yu-jiao, Liu, Lu, Nie, Mu, Hou, Yu, Wang, Ling, Li, Ban-ban, Xu, Miao, Teng, Qing-liang, Peng, Jun, Hou, Ming, Shi, Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855704/
https://ncbi.nlm.nih.gov/pubmed/33552061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.603278
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