Immunoproteasome subunit LMP7 Deficiency Improves Obesity and Metabolic Disorders

Inflammation plays an important role in the development of obesity and metabolic disorders; however, it has not been fully understood how inflammation occurs and is regulated in their pathogenesis. Low-molecular mass protein-7 (LMP7) is a proteolytic subunit of the immunoproteasome that shapes the r...

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Udgivet i:Sci Rep
Main Authors: Kimura, Hiroaki, Usui, Fumitake, Karasawa, Tadayoshi, Kawashima, Akira, Shirasuna, Koumei, Inoue, Yoshiyuki, Komada, Takanori, Kobayashi, Motoi, Mizushina, Yoshiko, Kasahara, Tadashi, Suzuki, Koichi, Iwasaki, Yusaku, Yada, Toshihiko, Caturegli, Patrizio, Takahashi, Masafumi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626825/
https://ncbi.nlm.nih.gov/pubmed/26515636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15883
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