NLRP3 Protein Deficiency Exacerbates Hyperoxia-induced Lethality through Stat3 Protein Signaling Independent of Interleukin-1β

Supplemental oxygen inhalation is frequently used to treat severe respiratory failure; however, prolonged exposure to hyperoxia causes hyperoxic acute lung injury (HALI), which induces acute respiratory distress syndrome and leads to high mortality rates. Recent investigations suggest the possible r...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Mizushina, Yoshiko, Shirasuna, Koumei, Usui, Fumitake, Karasawa, Tadayoshi, Kawashima, Akira, Kimura, Hiroaki, Kobayashi, Motoi, Komada, Takanori, Inoue, Yoshiyuki, Mato, Naoko, Yamasawa, Hideaki, Latz, Eicke, Iwakura, Yoichiro, Kasahara, Tadashi, Bando, Masashi, Sugiyama, Yukihiko, Takahashi, Masafumi
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2015
Ämnen:
Molecular Bases of Disease
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335242/
https://ncbi.nlm.nih.gov/pubmed/25548278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.603217
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