The Immunoproteasome Subunits LMP2, LMP7 and MECL-1 Are Crucial Along the Induction of Cerebral Toxoplasmosis

Cell survival and function critically relies on the fine-tuned balance of protein synthesis and degradation. In the steady state, the standard proteasome is sufficient to maintain this proteostasis. However, upon inflammation, the sharp increase in protein production requires additional mechanisms t...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: French, Timothy, Israel, Nicole, Düsedau, Henning Peter, Tersteegen, Anne, Steffen, Johannes, Cammann, Clemens, Topfstedt, Eylin, Dieterich, Daniela, Schüler, Thomas, Seifert, Ulrike, Dunay, Ildiko Rita
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099150/
https://ncbi.nlm.nih.gov/pubmed/33968021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.619465
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