The Immunoproteasome Subunits LMP2, LMP7 and MECL-1 Are Crucial Along the Induction of Cerebral Toxoplasmosis

Cell survival and function critically relies on the fine-tuned balance of protein synthesis and degradation. In the steady state, the standard proteasome is sufficient to maintain this proteostasis. However, upon inflammation, the sharp increase in protein production requires additional mechanisms t...

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Bibliografische gegevens
Gepubliceerd in:Front Immunol
Hoofdauteurs: French, Timothy, Israel, Nicole, Düsedau, Henning Peter, Tersteegen, Anne, Steffen, Johannes, Cammann, Clemens, Topfstedt, Eylin, Dieterich, Daniela, Schüler, Thomas, Seifert, Ulrike, Dunay, Ildiko Rita
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
Onderwerpen:
Immunology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099150/
https://ncbi.nlm.nih.gov/pubmed/33968021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.619465
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