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Cross-competition of CD8(+) T cells shapes the immunodominance hierarchy during boost vaccination
CD8(+) T cell responses directed against multiple pathogen-derived epitopes are characterized by defined immunodominance hierarchy patterns. A possible explanation for this phenomenon is that CD8(+) T cells of different specificities compete for access to epitopes on antigen-presenting cells, and th...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118691/ https://ncbi.nlm.nih.gov/pubmed/17709425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070489 |
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