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Treg Selectively Control CD8+ T Cell Effector Pool Size via IL-2 Restriction

Treg are key players in maintaining immunhomeostasis but have also been shown to regulate immune responses against infectious pathogens. Therefore Treg are a promising target for modulating immune responses to vaccines in order to improve their efficacy. Using a viral vector system, we found that Tr...

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Detalhes bibliográficos
Main Authors: Kastenmuller, Wolfgang, Gasteiger, Georg, Subramanian, Naeha, Sparwasser, Tim, Busch, Dirk H., Belkaid, Yasmine, Drexler, Ingo, Germain, Ronald N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169715/
https://ncbi.nlm.nih.gov/pubmed/21849683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101649
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