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Influenza A Virus Hemagglutinin Trimerization Completes Monomer Folding and Antigenicity

Influenza A virus (IAV) remains an important human pathogen largely because of antigenic drift, the rapid emergence of antibody escape mutants that precludes durable vaccination. The most potent neutralizing antibodies interact with cognate epitopes in the globular “head” domain of hemagglutinin (HA...

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Detalhes bibliográficos
Main Authors: Magadán, Javier G., Khurana, Surender, Das, Suman R., Frank, Gregory M., Stevens, James, Golding, Hana, Bennink, Jack R., Yewdell, Jonathan W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754138/
https://ncbi.nlm.nih.gov/pubmed/23824811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00471-13
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