Glycan-Dependent Immunogenicity of Recombinant Soluble Trimeric Hemagglutinin

Recombinant soluble trimeric influenza A virus (IAV) hemagglutinin (sHA(3)) has proven an effective vaccine antigen against IAV. Here, we investigate to what extent the glycosylation status of the sHA(3) glycoprotein affects its immunogenicity. Different glycosylation forms of subtype H5 trimeric HA...

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Bibliographic Details
Main Authors:	de Vries, Robert P., Smit, Cornelis H., de Bruin, Erwin, Rigter, Alan, de Vries, Erik, Cornelissen, Lisette A. H. M., Eggink, Dirk, Chung, Nancy P. Y., Moore, John P., Sanders, Rogier W., Hokke, Cornelis H., Koopmans, Marion, Rottier, Peter J. M., de Haan, Cornelis A. M.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology 2012
Subjects:	Vaccines and Antiviral Agents
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3486279/ https://ncbi.nlm.nih.gov/pubmed/22915811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01084-12
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Glycan-Dependent Immunogenicity of Recombinant Soluble Trimeric Hemagglutinin

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