Glycan-Dependent Immunogenicity of Recombinant Soluble Trimeric Hemagglutinin

Recombinant soluble trimeric influenza A virus (IAV) hemagglutinin (sHA(3)) has proven an effective vaccine antigen against IAV. Here, we investigate to what extent the glycosylation status of the sHA(3) glycoprotein affects its immunogenicity. Different glycosylation forms of subtype H5 trimeric HA...

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書誌詳細
主要な著者: de Vries, Robert P., Smit, Cornelis H., de Bruin, Erwin, Rigter, Alan, de Vries, Erik, Cornelissen, Lisette A. H. M., Eggink, Dirk, Chung, Nancy P. Y., Moore, John P., Sanders, Rogier W., Hokke, Cornelis H., Koopmans, Marion, Rottier, Peter J. M., de Haan, Cornelis A. M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2012
主題:
Vaccines and Antiviral Agents
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486279/
https://ncbi.nlm.nih.gov/pubmed/22915811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01084-12
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