Protective Efficacy of Newcastle Disease Virus Expressing Soluble Trimeric Hemagglutinin against Highly Pathogenic H5N1 Influenza in Chickens and Mice

BACKGROUND: Highly pathogenic avian influenza virus (HPAIV) causes a highly contagious often fatal disease in poultry, resulting in significant economic losses in the poultry industry. HPAIV H5N1 also poses a major public health threat as it can be transmitted directly from infected poultry to human...

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Autores principales: Cornelissen, Lisette A. H. M., de Leeuw, Olav S., Tacken, Mirriam G., Klos, Heleen C., de Vries, Robert P., de Boer-Luijtze, Els A., van Zoelen-Bos, Diana J., Rigter, Alan, Rottier, Peter J. M., Moormann, Rob J. M., de Haan, Cornelis A. M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429475/
https://ncbi.nlm.nih.gov/pubmed/22952980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044447
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