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Identification of a Linear Peptide Recognized by Monoclonal Antibody 2D7 Capable of Generating CCR5-Specific Antibodies with Human Immunodeficiency Virus-Neutralizing Activity

CCR5 is the major coreceptor for human immunodeficiency virus (HIV) infection. The murine monoclonal antibody (MAb) 2D7, which recognizes a conformation-dependent epitope in the second extracellular loop of CCR5, is one of the most potent inhibitors of R5 virus cell entry. However, attempts to human...

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Detaylı Bibliyografya
Asıl Yazarlar: Khurana, Surender, Kennedy, Michael, King, Lisa R., Golding, Hana
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1112162/
https://ncbi.nlm.nih.gov/pubmed/15890918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.11.6791-6800.2005
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